Researchers Discovered A Potential Novel Approach To Battle Rheumatoid Arthritis

Potential new approach to combat the inflammation, joint pain and tissue damage that are caused by rheumatoid arthritis has been recognized by the researchers from the Washington State University.

Science Daily reports that the study was issued on the Arthritis and Rheumatology, a journal of the American College of Rheumatology on Feb. 16. The study is led by Salah-Uddin-Ahmed, a researcher at Washington University.

Ahmed and his team analyzed a phytochemical that is referred to as epigallocatetechin-3-gallate (EGCG). This is a molecule that has anti-inflammatory properties and can be found in green tea.  

Green tea is made from unfermented leaves called Camellia Sinensis that have a slightly bitter flavor. It is originated in China and also produced in Japan.

The researchers found out that EGCG has an increased level of potential to treat rheumatoid arthritis because this molecule impedes the effects of the condition without stopping other cellular functions.

"This study has opened the field of research into using EGCG for targeting TAK1 -- an important signaling protein through which proinflammatory cytokines transmit their signals to cause inflammation and tissue destruction in rheumatoid arthritis," Ahmed said.

The findings were supported by a pre-clinical animal model of rheumatoid arthritis wherein they examined the inflammation of ankle in animals that were given EGCG in 10 days treatment. The results display reduces in the effects of rheumatoid arthritis.

WebMD describes Rheumatoid Arthritis as the inflammation of joint. It affects the joint on both hands, both knees and both wrists. The inflammation of the joint is caused by swelling, pain within the joint, warmth and redness.

The symptoms of rheumatoid arthritis include fatigue, joint pain, swelling and stiffness, particularly in a prolonged sitting. This medical condition is more common in women than in men. Its causes were not yet identified by the physicians. Rheumatoid Arthritis can be treated through medication, exercises, rest and for some cases; surgery is performed for joint damage.

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